Peripheral Neuropathy Management Peripheral neuropathy is a condition caused by damage to the peripheral nerves, leading to symptoms such as numbness, tingling, burning pain, weakness, or loss of sensation—most commonly in the hands and feet. Effective management focuses on identifying the underlying cause, relieving symptoms, and preventing further nerve damage. Causes of Peripheral Neuropathy Diabetes (most common cause) Vitamin deficiencies (especially B12) Infections and autoimmune disorders Toxins, alcohol, and certain medications Genetic and metabolic conditions